ISCTM 2009 5th Annual Scientific Meeting
Poster Awardees: (View posters by clicking on title) |
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| J. Calabrese: “Knowing When a Drug is Not Going to Work in Bipolar Depression”: Absence of Early Improvement as a Predictor of Later Non-Response in 3,369 Patients From 10 Placebo-Controlled Acute Trials | ||
| D. Daniel: Regional and Temporal Differences in Use of Doctorate Level MADRS Raters in Bipolar Depression Trials (All poster abstracts are available for public viewing. Link found at end of Day 2) |
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Related Publications: |
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AC Leon |
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Presentations and Videos:Day 1 (3 March 2009) |
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| President’s WELCOME | G Gharabawi slides |
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| SESSION 1: Development of Treatments for Bipolar Depression SUMMARY OF SESSION |
Chairs: R Baldessarini E Vieta |
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| Introduction and Objectives | E Vieta | |
| Bipolar Versus Unipolar Depression | ||
| Challenges to Design of Treatment Trials for Bipolar Depression: An International Perspective | E Vieta slides video |
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| Methodological Challenges in Short-term Treatment Trials for Bipolar Depression | M Tohen slides video |
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| Methodological Challenges in Long-term Treatment Trials for Bipolar Depression | J Calabrese slides video |
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| Panel and General Discussion: Treatment Trials for Bipolar Depression | ||
| Session Discussion - Q&A | video |
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Day 2 (4 March 2009) |
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| SESSION 2: Improving Methodology of RCTs for PTSD SUMMARY OF SESSION |
Chairs: A Leon L Davis |
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| Introduction to Session | L Davis video |
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| National Priorities for PTSD RCT Research | T O'Leary slides video |
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| Consideration of PTSD Nosology and Pathophysiology in Targeting the Study Population, Intervention, and Outcomes | L Davis slides video |
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| Psychotherapy Methodological Issues: Choice of Comparison Group | A Suris slides video |
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| Methodology for Evaluating Moderators of PTSD Treatment | A Leon slides video |
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| Methodological Challenges for Secondary Prevention Trials in PTSD | T Neylan slides video |
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| Session Discussion - Q&A | video |
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| SESSION 3: Recent FDA Decisions on Approval of Antipsychotics: A Redefinition of Risk - Benefit Assessment? SUMMARY OF SESSION |
Chairs: L Alphs R Anand |
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| Introduction: Objectives of Session | R Anand* |
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| Active Controls in Antipsychotic Trials: Why Have Them? | A Kalali slides video |
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| The Role of Active Controls for Risk-Benefit Analysis in Antipsychotic Clinical Trials: Clinical/Academic Considerations | J Lieberman slides video |
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| Discussion video |
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| Challenges and Implications of Use of Active Controls in Risk-Benefit Analysis in CNS Clinical Development Programs: An Industry Perspective | L Alphs slides video |
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| Implications of Use of Active Controls in Risk-Benefit Analysis in CNS Clinical Development Programs: Statistical Considerations | A Leon slides video |
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| Regulatory Policy Considerations on Risk-Benefit Assessment in CNS Clinical Trials and Benefit Challenges Identified in Recent New Drug Applications for Antipsychotic Drugs | T Laughren* |
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| Requirements on Medicinal Products in the Treatment of Schizophrenia – European Perspective | K Broich slides video |
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| Summary | R Anand | |
| Poster Session | View All Poster Abstracts | |
Day 3 (5 March 2009) |
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| Welcome from ASENT and ISCTM Presidents video |
R Porter L Alphs |
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| SESSION 4: Methodological Issues in Examining Cognition Across the CNS Spectrum SUMMARY OF SESSION |
Chairs: R Keefe S Rao |
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| Introduction: Cognition as an Under-Explored Aspect of Multiple Disorders | ||
| Cognitive Profiles, Assessment Challenges, and Efforts Towards Advancement in Selected Example Disorders | ||
| Schizophrenia: MATRICS and Beyond | M Green slides video |
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| Multiple Sclerosis: Psychometric Considerations and Consensus Standards | R Benedict slides video |
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| Epilepsy: Cognitive and Behavioral Endpoints as Primary Outcome Variables | D Loring slides video |
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| Bipolar Disorder: Application of Cognitive Assessment Methods | K Burdick slides video |
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| Structured Discussion | ||
| Regulatory Perspective: Neurological Conditions | R Katz | |
| Regulatory Perspective: Psychiatric Conditions | T Laughren | |
| Panel | R Benedict K Burdick M Green R Katz R Keefe T Laughren D Loring G Tucker |
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| Summary and Recommendations | R Keefe S Rao |
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SESSION 5: Methodological Issues In Traumatic Brain Injury
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Chairs: A Faden slides videoT Macek |
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| Characterization and Changes in Civilian Populations | M Lovell slides video |
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| Characterization and Challenges in Military Populations | ||
| Studies of Acute mTBI in the Combat Arena | M Jaffee slides video |
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| Studies of Chronic Problems After mTBI | K Schwab slides video |
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| Methodological Issues and Translational Research in TBI | ||
| Mechanisms of Mild TBI | D Smith slides video |
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| Methodological Problems in TBI Trials | R Bullock slides video |
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| Discussion - Q&A video Discussion - Q&A (continued) video |
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| Summary | T Macek | |
| Dinner Symposium: Resource Allocation in Translational Neuroscience: Perspectives on Influencing the Pipeline | Chairs: R Ferziger K Clarence-Smith |
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| Tom Insel, MD, NIMH slides |
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| Janet Vergis, Janssen, A Division of Ortho-McNeil Janssen Pharmaceuticals slides |
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| Jonathan Fleming, Oxford Biosciences slides |
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| Adjourn | ||
| * Presentation materials have not as yet been released for publication in this forum. | ||
Journal of Clinical Psychiatry (in press)